A blood-based approach could enable personalized immunotherapy without the need for a tumor biopsy

🌐 Medical Xpress (Isle of Man) —
A blood-based approach could enable personalized immunotherapy without the need for a tumor biopsy

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Researchers report identifying cancer neoantigens and matching immune cells from patients’ blood samples, using circulating tumor DNA and immune-cell analysis. The approach could support personalized immunotherapy without requiring a tumor biopsy.

In a study published in Cancer Discovery, cancer neoantigens and neoantigen-specific T cells were identified from patient blood samples by analyzing circulating tumor DNA (ctDNA) and immune cells.

World Health cancer immunotherapy neoantigens blood samples ctDNA biopsy-free testing precision medicine

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