[Articles] Endovascular thrombectomy for patients with large-core ischaemic stroke presenting up to 24 h after onset (ATLAS): a systematic review and individual patient data meta-analysis with central imaging adjudication

AI Summary

A study reviewing endovascular thrombectomy for ischaemic stroke patients shows it leads to better outcomes compared to medical management. Results indicate sustained benefits for patients presenting up to 24 hours after onset, although limitations exist for those with extensive ischaemic changes.

Endovascular thrombectomy was associated with improved functional outcomes and reduced mortality versus medical management in patients with large-core ischaemic stroke presenting within 24 h of onset. With the exception of very extensive ischaemic changes (core volume ≥150 mL) presenting beyond 6 h, where evidence remains limited, benefit was sustained across ASPECTS and ischaemic core strata for patients presenting up to 24 h after onset.