Experimental drug eliminates 75% of aggressive pancreatic tumors and enhances immune system memory

AI Summary

The article describes an experimental drug approach targeting the scar-like tissue that can shield solid tumors from immune attack. In reported research, the treatment eliminated 75% of aggressive pancreatic tumors and improved immune-system memory, potentially addressing a barrier to immunotherapy.

Many solid tumors, including many cancers of the pancreas, breast, colon and lung, protect themselves with a dense wall of scar-like tissue. That wall keeps the immune system's cancer-killing T cells out. It is a major reason why immunotherapy drugs, which have transformed treatment for some patients, help only a minority of people with solid tumors.