Fractionated radiosurgery reduces cancer recurrence after surgery for large brain metastases

AI Summary

A randomized Phase III trial found that delivering focused radiation over three to five sessions after surgery reduced local recurrence of large brain metastases compared with a single-session treatment. The findings support fractionated radiosurgery as a postoperative option for these patients.

Delivering focused radiation therapy over three to five sessions after surgery for a large brain metastasis reduced the risk of cancer returning at the surgical site compared with delivering the radiation in a single session, according to the first randomized Phase III clinical trial directly comparing the approaches.