NICE recommends single saliva test to speed up diagnosis of endometriosis in primary care

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The UK National Institute for Health and Care Excellence recommends a saliva-based test called Endotest to aid primary care diagnosis of suspected endometriosis, while other diagnostic technologies remain under consideration or require further research.

A saliva based diagnostic test, called Endotest, can be used in primary care when endometriosis is suspected, the UK National Institute of Health and Care Excellence (NICE) has recommended in updated draft guidance.1An original version of the draft guidance, published in July, recommended two non-invasive tests to speed up the diagnosis of endometriosis, Endotest and Endosure.2However, after consideration of consultation responses alongside the original evidence base, the committee has now concluded that the evidence for Endosure remains too limited to be recommended.Endosure attempts to detect endometriosis by using sensor pads on the abdomen to measure electrical signals in the gut.More research is also needed before two blood tests, DotEndo and Endomkit, can be considered for NHS funding, NICE added.Endotest is a test that detects a biomarker signature of endometriosis in saliva. The saliva sample must be sent to a lab for analysis. NICE recommends its use in primary care when...