Nick Bosa Injury Update: 49ers DE Could Miss Multiple Weeks With ‘Serious Injury’

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San Francisco 49ers defensive end Nick Bosa has suffered a calf injury during practice, expected to miss multiple weeks in the 2026 season. This injury setback compounds his previous ACL injury, affecting the defensive lineup early in the NFL season.

Nick Bosa’s return from last season’s ACL injury has taken another difficult turn. The San Francisco 49ers defensive end is now expected to miss multiple weeks after suffering a calf injury in practice, putting his availability on hold just two games into the 2026 season. The timing is especially rough for the 49ers defense already […] The post Nick Bosa Injury Update: 49ers DE Could Miss Multiple Weeks With ‘Serious Injury’ appeared first on Gridiron Heroics.