TROP2 marks relapse-driving colorectal cancer cells and opens path to targeted treatment

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Researchers from the German Cancer Research Center and HI-STEM Stem Cell Institute identified the Trop2 marker, which drives relapse in aggressive colorectal cancer cells, opening pathways for targeted treatment strategies.

A team led by researchers from the German Cancer Research Center (DKFZ) and the HI-STEM Stem Cell Institute has discovered a promising new approach to treating advanced colorectal cancer. The study, published in Nature, identifies a key marker of particularly aggressive and treatment-resistant colorectal cancer cells.